If you want it to work directly with protools you need one of the M-audio models & Protools M-powered. But you allready have an M-box so i suggest you get a new little mackie analog mixer.. Cant go wrong.. Really depends what you want to do and how many channels you need..

your request is a bit vague, sound slike price might be driving you here, but maybe I can help a bit.

First off, Digi has ProTools setup to only work with proprietary hardware, so you need a Digi product or M-Audio (but then you need the MPowered version of ProTools). The Digi 003 comes in a mixer format, I believe called Factory, but its pretty steep $$$.

I wouldn't expect much out of an Alesis or a Phonics, generally speaking you're going to get what you pay for in terms of quality and reliability, so sometimes spending the extra $$ now will save you more $$$ in the future.

Do you need a mixer? Is it because you need the extra channels? Maybe you should consider a firewire interface (the Digi002 should be reasonably priced by now) and an external mixer routed in. IMHO these all-in-one solutions for mixing, preamps and conversion tend to be a little cheap if you're in the under $1000 price range.

Your mileage may vary...

How much do you want to spend? How many channels do you need to record simultaneously? Are you an acoustic musician or an electronic one? All of these factors will influence your decision. At this moment, there are a few options. I think a frontrunner would be the TC Electronic Konnekt 24D. It is a VERY highly rated audio/MIDI interface, with a pristine signal path, great mic pre's, built in high-quality effects, and all for about $500 (...on Musicians Friend. $529 for one with an AKG Perception 200 condenser mic thrown in. Quite a deal. I think I'm about to buy this myself). The M-Audio NRV-10 sounds compelling as well. All those inputs sound really tempting (not as high a sample rate, though). And it's got some great functionality & routing options (plus the obvious live applications). The NRV-10 has the added bonus of being compatible with Pro-Tools MPowered (which is pretty much LE). There are some really good reviews on each of these units which I can send you, if you're interested. Outside of these choices, I would also consider the Presonus Firepod. I tend to be of the opinion that the MOTU gear, though highly respected, is a bit expensive when compared to the competitors. If you'd like more information, let me know.